GHRP-6 (10 mg Vial) Dosage Protocol
GHRP-6 is the original GHRP, producing GH release alongside marked appetite stimulation through ghrelin pathway activation.
⚡ Quickstart Highlights
Dosing & Reconstitution Guide
Route: Subcutaneous | Frequency: 3× daily | Half-life: ~30 minutes
Standard Approach (3 mL = 3.33 mg/mL)
Reconstituting with 3 mL bacteriostatic water produces a concentration of 3.33 mg/mL. Volume per dose changes with concentration; mg dose itself does not change between vial sizes.
| Phase / Protocol | Dose | U-100 Units | Volume | Doses per vial |
|---|---|---|---|---|
| Weeks 1–2 (titration) | 100 mcg | 3 units | 0.030 mL | 100 doses |
| Weeks 3–4 | 200 mcg | 6 units | 0.060 mL | 50 doses |
| Weeks 5–12 (target) | 300 mcg | 9 units | 0.090 mL | 33 doses |
Reconstitution Steps
- Wipe the vial stopper and BAC water vial with alcohol; let dry.
- Draw 3 mL of bacteriostatic water into a sterile syringe.
- Inject slowly down the inside glass wall of the peptide vial. Do not aim at the powder.
- Gently swirl until fully dissolved. Do not shake.
- Label with reconstitution date. Refrigerate at 2–8°C; use within 7 days.
Supplies Needed
Estimates for an 8-week and 12-week cycle at 200 mcg per dose, 3× daily (3 doses/week).
| Item | 8-Week Cycle | 12-Week Cycle |
|---|---|---|
| GHRP-6 (10 mg) vials | 1 vials | 1 vials |
| Insulin syringes (U-100) | 24 | 36 |
| Bacteriostatic water (10 mL) | 1 × 10 mL | 1 × 10 mL |
| Alcohol swabs | 1 × 100-pack | 2 × 100-pack |
Protocol Overview
GHRP-6 is the most appetite-stimulating GHRP — the ghrelin pathway activation produces dramatic hunger about 30–60 minutes after dosing. This makes it suitable for protocols where weight gain or appetite recovery is desired (e.g., post-illness, hard-gainer support).
Dosing Protocol
Daily dosing:
- Light (100 mcg, once daily): Single pulse.
- Standard (150 mcg, 2–3× daily): Common research dose.
Cycle structure: 8–12 weeks active, then 4-week break.
Timing: Plan meals to leverage the appetite stimulation — dose 30–60 min before scheduled meal times if weight gain is the goal.
Storage Instructions
| State | Temperature | Duration |
|---|---|---|
| Lyophilized | −20°C (−4°F) | Up to 24 months, dry & dark |
| Reconstituted | 2–8°C (35–46°F) | Up to 7 days, protect from light |
Important Notes
How This Works
GHRP-6 was the first widely studied GHRP. It binds GHS-R1a triggering GH release. Compared to ipamorelin and GHRP-2, GHRP-6 produces the strongest appetite stimulation via ghrelin pathway activation. It also elevates cortisol and prolactin modestly.
Potential Benefits & Side Effects
Potential Benefits
- Strong GH pulse plus appetite stimulation (useful in some protocols).
- Established literature spanning decades.
Side Effect Profile
- Marked appetite increase (most pronounced of the GHRPs).
- Cortisol and prolactin elevation.
- Mild fluid retention.
- Injection-site reactions.
Lifestyle Factors
- Plan meals to manage appetite stimulation.
- Avoid eating immediately after dosing.
Injection Technique
- Subcutaneous into abdomen, thigh, or upper arm. Rotate sites.