Epitalon Dosage Protocols: All Vial Sizes
Epitalon is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) developed from the pineal gland peptide Epithalamin. Russian research groups have studied it for telomere maintenance and longevity outcomes. Choose your vial size below; each size has its own exact dosing table.
Choose Your Vial Size
| Vial | Final volume | Concentration | One U-100 unit | |
|---|---|---|---|---|
| 10 mg | 2 mL | 5 mg/mL | 50 mcg in 0.01 mL | Open protocol → |
| 50 mg | 2 mL | 25 mg/mL | 250 mcg in 0.01 mL | Open protocol → |
Doses are the same research amounts across sizes; the vial size changes the concentration, so syringe units differ. Always use the table for your exact vial.
Storage Instructions
| State | Temperature | Duration |
|---|---|---|
| Lyophilized | −20°C (−4°F) | Up to 24 months, dry & dark |
| Reconstituted | 2–8°C (35–46°F) | Up to 30 days, protect from light |
Important Notes
How This Works
Epitalon is a synthetic tetrapeptide derived from Epithalamin, originally identified by Vladimir Khavinson's group. Reported actions include telomerase upregulation in human somatic cell culture, restoration of pineal melatonin secretion toward youthful patterns, normalization of disrupted circadian cortisol rhythms, and gene-expression modulation in immune and neuroendocrine tissues.
Potential Benefits & Side Effects
Potential Benefits
- Reported telomerase upregulation in cell culture.
- Restoration of melatonin secretion patterns in elderly.
- Normalization of disrupted circadian rhythms.
- Russian observational studies report mortality reduction in elderly cohorts.
- Antioxidant effects via gene-expression modulation.
Side Effect Profile
- Generally well-tolerated.
- Mild injection-site reactions.
- Vivid dreams reported.
Lifestyle Factors
- Cycle-based dosing — typical 10–20 day cycle, 1–2× per year.
- Evening dosing aligns with pineal/melatonin axis.
- Pair with circadian-aligned light exposure.
Injection Technique
- Subcutaneous, rotate sites if dosing daily during cycle.