DSIP (Delta Sleep-Inducing Peptide) Dosage Protocols: All Vial Sizes
DSIP is a 9-amino-acid neuropeptide first isolated from rabbit cerebral venous blood during electrically induced sleep. It modulates delta-wave sleep and exhibits anti-stress effects. Choose your vial size below; each size has its own exact dosing table.
Choose Your Vial Size
| Vial | Final volume | Concentration | One U-100 unit | |
|---|---|---|---|---|
| 5 mg | 3 mL | 1.67 mg/mL | 16.67 mcg in 0.01 mL | Open protocol → |
| 15 mg | 3 mL | 5 mg/mL | 50 mcg in 0.01 mL | Open protocol → |
Doses are the same research amounts across sizes; the vial size changes the concentration, so syringe units differ. Always use the table for your exact vial.
Storage Instructions
| State | Temperature | Duration |
|---|---|---|
| Lyophilized | −20°C (−4°F) | Up to 24 months, dry & dark |
| Reconstituted | 2–8°C (35–46°F) | Up to 30 days, protect from light |
Important Notes
How This Works
DSIP (Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu) was first isolated from venous blood of rabbits during electrically induced sleep. Despite its name it does not directly induce sleep but appears to modulate sleep architecture, particularly delta-wave activity. It modulates the HPA axis with cortisol-lowering effects under stress, alters limbic neurotransmitter release, and exerts antioxidant and anti-convulsant activity.
Potential Benefits & Side Effects
Potential Benefits
- Modulation of slow-wave sleep architecture.
- Anti-stress via HPA axis modulation — reduced cortisol.
- Anxiolytic and mild analgesic in animal models.
- Antioxidant effects on brain tissue.
Side Effect Profile
- Generally well-tolerated.
- Mild injection-site discomfort.
- Vivid dreams reported.
- Daytime drowsiness if dosed too late.
Lifestyle Factors
- Inject 30–60 minutes before bedtime in a calm setting.
- Consistent sleep-wake schedule for best results.
- Avoid screens, caffeine, alcohol within 2 hours of dosing.
- Effects accumulate — many users report results after 1–2 weeks.
Injection Technique
- Subcutaneous, rotate sites if dosing nightly.
- Pre-bedtime timing is universal — DSIP is short-acting.