Vesugen (20 mg Vial) Dosage Protocol
Vesugen (Lys-Glu-Asp) is a synthetic tripeptide bioregulator targeting vascular endothelium, studied in Russian protocols for vascular health, endothelial repair, and cardiovascular support.
⚡ Quickstart Highlights
Dosing & Reconstitution Guide
Educational guide for reconstitution and daily dosing
Standard / Gradual Approach (3 mL = ~6.67 mg/mL)
| Week | Daily Dose (mcg) | Units (per injection) (mL) |
|---|---|---|
| Week 1 | 500 mcg (0.5 mg) | 7.5 units (0.075 mL) |
| Week 2 | 1000 mcg (1.0 mg) | 15 units (0.15 mL) |
| Week 3 | 1500 mcg (1.5 mg) | 22.5 units (0.225 mL) |
| Weeks 4–8+ | 1500–2000 mcg (1.5–2.0 mg) | 22.5–30 units (0.225–0.30 mL) |
Frequency: Inject once daily subcutaneously. For ≤10-unit (≤0.10 mL) administrations, consider 30- or 50-unit insulin syringes for improved readability. Note that Week 1 dosing falls at 7.5 units; a 50-unit syringe with 0.5-unit graduations improves accuracy.
Reconstitution Steps
- Draw 3.0 mL bacteriostatic water with a sterile syringe.
- Inject slowly down the vial wall; avoid foaming.
- Gently swirl/roll until dissolved (do not shake).
- Label and refrigerate at 2–8 °C (35.6–46.4 °F), protected from light.
Important: This guide is for educational purposes only and is not medical advice. For research use only. Not for human consumption.
Supplies Needed
Plan based on an 8–16 week daily protocol with gradual titration (targeting ~1500 mcg/day maintenance).
| Item | Quantity |
|---|---|
| Peptide Vials (Vesugen, 20 mg each) | 8 weeks (~84 mg total) ≈ 5 vials 12 weeks (~126 mg total) ≈ 7 vials 16 weeks (~168 mg total) ≈ 9 vials |
| Insulin Syringes (U-100) | Per week: 7 syringes (1/day) 8 weeks: 56 syringes 12 weeks: 84 syringes 16 weeks: 112 syringes |
| Bacteriostatic Water (10 mL bottles) | 8 weeks (5 vials): 15 mL → 2 × 10 mL bottles 12 weeks (7 vials): 21 mL → 3 × 10 mL bottles 16 weeks (9 vials): 27 mL → 3 × 10 mL bottles |
| Alcohol Swabs | Per week: 14 swabs (2/day) 8 weeks: 112 swabs → recommend 2 × 100-count boxes 12 weeks: 168 swabs → recommend 2 × 100-count boxes 16 weeks: 224 swabs → recommend 3 × 100-count boxes |
Protocol Overview
The hypothesized gene-expression mechanism produces effects that persist months after the cycle ends, supporting the cycled rather than continuous approach. Evidence base is primarily Russian gerontology and clinical research; peer-reviewed Western data is limited.
Storage Instructions
| State | Temperature | Duration |
|---|---|---|
| Lyophilized | −20°C (−4°F) | Up to 24 months, dry & dark |
| Reconstituted | 2–8°C (35–46°F) | Up to 30 days, protect from light |
Important Notes
How This Works
Vesugen is a Khavinson-class peptide bioregulator hypothesized to support endothelial gene expression, nitric oxide synthesis, and vascular tone regulation.
Potential Benefits & Side Effects
Potential Benefits
- Vascular endothelial support in Russian clinical protocols.
- Studied for cardiovascular aging.
- May pair with lifestyle cardiovascular interventions.
Side Effect Profile
- Generally well-tolerated in Russian clinical literature.
- Mild injection-site reactions.
- Limited peer-reviewed Western data.
Lifestyle Factors
- Adequate sleep and rest during cycles.
- Balanced nutrition supports cellular repair.
Injection Technique
- Subcutaneous, rotate sites daily during 20-day cycle.