SLU-PP-332 (10 mg Vial) Dosage Protocol
SLU-PP-332 is a small-molecule AMPK activator (5-aminoimidazole-4-carboxamide ribonucleotide) studied as an exercise mimetic in metabolic research.
⚡ Quickstart Highlights
Dosing & Reconstitution Guide
Educational guide based on published murine regimens
Murine-Equivalent Protocol (3 mL = 3.33 mg/mL)
| Phase | Daily Dose (mcg) | Per-Injection Dose (mcg) | Units per Injection (mL) |
|---|---|---|---|
| Weeks 1–2 | 1250 mcg | 625 mcg | 18.75 units (0.188 mL) |
| Weeks 3–8 | 2500 mcg | 1250 mcg | 37.5 units (0.375 mL) |
Route & Frequency: Published murine studies used intraperitoneal administration twice daily (25–50 mg/kg). Daily mcg values above are expressed for a 25 g mouse. No reputable sources support once-daily subcutaneous use for this compound.
Reconstitution Steps
- Draw 3 mL bacteriostatic water with a sterile syringe.
- Inject slowly down the vial wall; avoid foaming.
- Gently swirl/roll until dissolved (do not shake).
- Label and refrigerate at 2–8 °C (35.6–46.4 °F), protected from light.
Critical: This guide reflects preclinical murine research only. This information is for educational and research purposes exclusively—not for human consumption. No human safety or efficacy data exist for SLU-PP-332.
Supplies Needed
Calculated from the schedule above for a 10 mg vial reconstituted with 3 mL (two injections per day, two swabs per injection).
| Item | 8 weeks | 12 weeks | 16 weeks |
|---|---|---|---|
| Peptide vials (10 mg each) | 13 vials (122.5 mg total) | 20 vials (192.5 mg total) | 27 vials (262.5 mg total) |
| Insulin syringes (U-100) | 112 syringes | 168 syringes | 224 syringes |
| Bacteriostatic water (10 mL bottles) | 39 mL → 4 × 10 mL bottles | 60 mL → 6 × 10 mL bottles | 81 mL → 9 × 10 mL bottles |
| Alcohol swabs | 224 swabs → 3 × 100-count boxes | 336 swabs → 4 × 100-count boxes | 448 swabs → 5 × 100-count boxes |
Protocol Overview
WADA prohibited list. Most research-grade use pairs with regular endurance training to amplify the AMPK-activation effects.
Storage Instructions
| State | Temperature | Duration |
|---|---|---|
| Lyophilized | −20°C (−4°F) | Up to 24 months, dry & dark |
| Reconstituted | 2–8°C (35–46°F) | Up to 30 days, protect from light |
Important Notes
How This Works
SLU-PP-332 is a small molecule (not strictly a peptide) that acts as an AMP-mimetic, activating AMP-activated protein kinase (AMPK). AMPK activation drives fatty-acid oxidation, mitochondrial biogenesis, and glucose uptake in skeletal muscle — mimicking exercise-induced metabolic adaptations.
Potential Benefits & Side Effects
Potential Benefits
- Pan-ERRα/β/γ activation → mitochondrial biogenesis.
- Endurance improvement without exercise in animal models.
- Fatty-acid oxidation upregulation.
Side Effect Profile
- Very limited human safety data available.
- Potentially metabolically active — monitor glucose.
Lifestyle Factors
- Human safety profile is not established — proceed with extreme caution.
- Animal data only; no human clinical trials completed.
Injection Technique
- Subcutaneous, rotate sites.