Pinealon (20 mg Vial) Dosage Protocol
Pinealon is a synthetic tetrapeptide (Glu-Asp-Arg) studied by Russian researchers as a brain-targeted bioregulator with neuroprotective and cognitive effects.
⚡ Quickstart Highlights
Dosing & Reconstitution Guide
Educational guide for reconstitution and daily dosing
Standard Approach (3 mL = ~6.67 mg/mL)
| Days | Daily Dose | Units (per injection) (mL) |
|---|---|---|
| Days 1–5 | 1.0 mg (1,000 mcg) | 15 units (0.15 mL) |
| Days 6–14 | 1.5 mg (1,500 mcg) | 22.5 units (0.225 mL) |
| Days 15–20 | 2.0 mg (2,000 mcg) | 30 units (0.30 mL) |
Frequency: Inject once daily subcutaneously, preferably in the morning or early afternoon. Standard cycles are 10–20 days, with the option to extend to 28 days if desired. Repeat cycles can be administered every 2–3 months as needed.
Reconstitution Steps
- Draw 3.0 mL bacteriostatic water with a sterile syringe.
- Inject slowly down the vial wall; avoid foaming.
- Gently swirl/roll until dissolved (do not shake).
- Label and refrigerate at 2–8 °C (35.6–46.4 °F), protected from light.
Important: This guide is for educational purposes only and is not medical advice. For research use only. Not for human consumption.
Supplies Needed
Plan based on standard 10–20 day cycles with once‑daily administration.
| Item | Quantity |
|---|---|
| Peptide Vials (Pinealon, 20 mg each) | 10‑day cycle ≈ 1 vial 20‑day cycle ≈ 2 vials 28‑day cycle ≈ 3 vials |
| Insulin Syringes (U‑100) | Per day: 1 syringe 10‑day cycle: 10 syringes 20‑day cycle: 20 syringes 28‑day cycle: 28 syringes |
| Bacteriostatic Water (10 mL bottles) | 10‑day cycle (1 vial): 3 mL → 1 × 10 mL bottle 20‑day cycle (2 vials): 6 mL → 1 × 10 mL bottle 28‑day cycle (3 vials): 9 mL → 1 × 10 mL bottle |
| Alcohol Swabs | Per day: 2 swabs 10‑day cycle: 20 swabs 20‑day cycle: 40 swabs 28‑day cycle: 56 swabs → recommend 1 × 100‑count box |
Protocol Overview
The hypothesized gene-expression-modulation mechanism produces effects that persist for months after the cycle ends.
Storage Instructions
| State | Temperature | Duration |
|---|---|---|
| Lyophilized | −20°C (−4°F) | Up to 24 months, dry & dark |
| Reconstituted | 2–8°C (35–46°F) | Up to 30 days, protect from light |
Important Notes
How This Works
Pinealon is a synthetic tripeptide bioregulator (Glu-Asp-Arg) developed by Khavinson's group. Like Epitalon, it is hypothesized to act via gene-expression modulation in target tissues — in this case brain cortex and hippocampus. Animal models show neuroprotective effects and improved cognitive performance after stress.
Potential Benefits & Side Effects
Potential Benefits
- Neuroprotective effects in animal stress models.
- Improvements in memory and learning in rodent studies.
- Antioxidant effects on neural tissue.
- Used in Russian protocols for age-related cognitive decline.
Side Effect Profile
- Generally well-tolerated.
- Mild injection-site reactions.
- Long-term human safety data outside Russian literature is limited.
Lifestyle Factors
- Cycle-based dosing — typical 10–20 day cycle, 1–2× per year.
- Pair with cognitive engagement (reading, learning) for compounding effect.
- Adequate sleep amplifies neuroprotective effects.
Injection Technique
- Subcutaneous, rotate sites during cycle.