GHRP-2 (5 mg Vial) Dosage Protocol
GHRP-2 is a 6-amino-acid GHRP that stimulates GH release via the ghrelin receptor. Older than ipamorelin but with broader activity including some cortisol and appetite stimulation.
⚡ Quickstart Highlights
Dosing & Reconstitution Guide
Educational guide for reconstitution and daily dosing
Standard / Gradual Approach (3 mL = ~1.67 mg/mL)
| Week | Daily Dose (mcg) | Units (per injection) (mL) |
|---|---|---|
| Weeks 1–2 | 100 mcg | 6 units (0.06 mL) |
| Weeks 3–4 | 150 mcg | 9 units (0.09 mL) |
| Weeks 5–8 | 200 mcg | 12 units (0.12 mL) |
| Weeks 9–12 | 200 mcg | 12 units (0.12 mL) |
| Weeks 13–16 | 200 mcg | 12 units (0.12 mL) |
Frequency: Inject once daily subcutaneously. This once-daily schedule balances efficacy with receptor recovery time, avoiding the rapid attenuation seen with frequent dosing. Administering in the evening may capitalize on nocturnal GH rhythms. For ≤10-unit (≤0.10 mL) administrations, consider 30- or 50-unit insulin syringes for improved readability.
Reconstitution Steps
- Draw 3.0 mL bacteriostatic water with a sterile syringe.
- Inject slowly down the vial wall; avoid foaming.
- Gently swirl or roll until completely dissolved (do not shake).
- Label and refrigerate at 2–8 °C (35.6–46.4 °F), protected from light.
Important: This guide is for educational purposes only and is not medical advice. For research use only. Not for human consumption.
Supplies Needed
Plan based on an 8–16 week daily protocol with gradual titration.
| Item | Quantity |
|---|---|
| Peptide Vials (GHRP-2, 5 mg each) | 8 weeks: approximately 2 vials required 12 weeks: approximately 4 vials required 16 weeks: approximately 5 vials required |
| Insulin Syringes (U-100) | Per week: 7 syringes (1/day) 8 weeks: 56 syringes 12 weeks: 84 syringes 16 weeks: 112 syringes |
| Bacteriostatic Water (10 mL bottles) | 8 weeks (2 vials): 6 mL — 1 bottle required (10 mL each) 12 weeks (4 vials): 12 mL — 2 bottles required (10 mL each) 16 weeks (5 vials): 15 mL — 2 bottles required (10 mL each) |
| Alcohol Swabs | Per week: 14 swabs (2/day) 8 weeks: 112 swabs — 2 boxes required (100 swabs each) 12 weeks: 168 swabs — 2 boxes required (100 swabs each) 16 weeks: 224 swabs — 3 boxes required (100 swabs each) |
Protocol Overview
Compared to ipamorelin it produces stronger GH pulses but with measurable cortisol and prolactin elevation, plus marked appetite stimulation via ghrelin pathway activation. The appetite effect makes it suitable for protocols where increased intake is desirable (e.g., bulking, post-illness weight gain).
Storage Instructions
| State | Temperature | Duration |
|---|---|---|
| Lyophilized | −20°C (−4°F) | Up to 24 months, dry & dark |
| Reconstituted | 2–8°C (35–46°F) | Up to 28 days, protect from light |
Important Notes
How This Works
GHRP-2 binds the ghrelin receptor (GHS-R1a) on pituitary somatotrophs, triggering GH release. Unlike ipamorelin, GHRP-2 also produces measurable cortisol and prolactin elevation and stimulates appetite via the ghrelin pathway.
Potential Benefits & Side Effects
Potential Benefits
- Strong GH pulse via ghrelin receptor.
- Useful in protocols where appetite stimulation is desired.
- Synergistic with GHRH analogs.
Side Effect Profile
- Cortisol and prolactin elevation.
- Significant appetite increase.
- Injection-site reactions.
- Mild fluid retention.
Lifestyle Factors
- Manage appetite stimulation with planned meals.
- Avoid eating for 30+ min post-dose.
- Resistance training to leverage GH pulse.
Injection Technique
- Subcutaneous into abdomen, thigh, or upper arm.
- Rotate sites with each dose.