Cortagen (20 mg Vial) Dosage Protocol
Cortagen (Ala-Glu-Asp-Pro) is a synthetic tetrapeptide bioregulator targeting the cerebral cortex, studied in Russian protocols for cognitive support, memory consolidation, and neural repair after ischemic events.
⚡ Quickstart Highlights
Dosing & Reconstitution Guide
Educational guide for reconstitution and daily dosing
Standard Approach (3 mL = 6.67 mg/mL)
| Week | Daily Dose (mcg) | Units (per injection) (mL) |
|---|---|---|
| Weeks 1–2 | 1000 mcg | 15 units (0.15 mL) |
| Weeks 3–4 | 2000 mcg | 30 units (0.30 mL) |
Frequency: Inject once daily subcutaneously, preferably in the morning. This schedule uses the largest practical dilution (3.0 mL) to keep per-injection units ≥15 for accurate measurement. For doses under ~10 units (<700 mcg), consider using 50-unit or 30-unit insulin syringes for improved readability.
Reconstitution Steps
- Draw 3.0 mL bacteriostatic water with a sterile syringe.
- Inject slowly down the vial wall; avoid foaming.
- Gently swirl/roll until dissolved (do not shake).
- Label and refrigerate at 2–8 °C (35.6–46.4 °F), protected from light.
Important: This guide is for educational purposes only and is not medical advice. For research use only. Not for human consumption.
Supplies Needed
Plan based on a 4-week daily protocol with gradual titration (1000–2000 mcg/day).
| Item | Quantity |
|---|---|
| Peptide Vials (Cortagen, 20 mg each) | 4 weeks ≈ 3 vials (at average 1500 mcg/day = 42 mg total) 8 weeks ≈ 5 vials |
| Insulin Syringes (U-100) | Per week: 7 syringes (1/day) 4 weeks: 28 syringes 8 weeks: 56 syringes |
| Bacteriostatic Water (10 mL bottles) | 4 weeks (3 vials): 9 mL → 1 × 10 mL bottle 8 weeks (5 vials): 15 mL → 2 × 10 mL bottles |
| Alcohol Swabs | Per week: 14 swabs (2/day) 4 weeks: 56 swabs → recommend 1 × 100-count box 8 weeks: 112 swabs → recommend 2 × 100-count boxes |
Protocol Overview
The hypothesized gene-expression mechanism produces effects that persist months after the cycle ends, supporting the cycled rather than continuous approach. Evidence base is primarily Russian gerontology and clinical research; peer-reviewed Western data is limited.
Storage Instructions
| State | Temperature | Duration |
|---|---|---|
| Lyophilized | −20°C (−4°F) | Up to 24 months, dry & dark |
| Reconstituted | 2–8°C (35–46°F) | Up to 30 days, protect from light |
Important Notes
How This Works
Cortagen is a Khavinson-class peptide bioregulator hypothesized to modulate gene expression in cortical neurons, supporting neurotrophic factor production and synaptic plasticity.
Potential Benefits & Side Effects
Potential Benefits
- Cognitive support and memory consolidation in Russian clinical protocols.
- Studied for post-stroke neural recovery.
- Pairs with other nootropic peptides in stacked protocols.
Side Effect Profile
- Generally well-tolerated in Russian clinical literature.
- Mild injection-site reactions.
- Limited peer-reviewed Western data.
Lifestyle Factors
- Adequate sleep and rest during cycles.
- Balanced nutrition supports cellular repair.
Injection Technique
- Subcutaneous, rotate sites daily during 20-day cycle.