BPC-157 Dosage Protocols: All Vial Sizes
BPC-157 (Body Protection Compound 157) is a 15-amino-acid peptide derived from a protective sequence in human gastric juice. Preclinical research demonstrates wide-ranging effects on tendon, ligament, gut, and vascular healing. Choose your vial size below; each size has its own exact dosing table.
Choose Your Vial Size
| Vial | Final volume | Concentration | One U-100 unit | |
|---|---|---|---|---|
| 5 mg | 3 mL | 1.67 mg/mL | 16.67 mcg in 0.01 mL | Open protocol → |
| 10 mg | 3 mL | 3.33 mg/mL | 33.33 mcg in 0.01 mL | Open protocol → |
| 20 mg | 3 mL | 6.67 mg/mL | 66.67 mcg in 0.01 mL | Open protocol → |
Doses are the same research amounts across sizes; the vial size changes the concentration, so syringe units differ. Always use the table for your exact vial.
Storage Instructions
| State | Temperature | Duration |
|---|---|---|
| Lyophilized | −20°C (−4°F) | Up to 24 months, dry & dark |
| Reconstituted | 2–8°C (35–46°F) | Up to 30 days, protect from light |
Important Notes
How This Works
BPC-157 is a synthetic 15-amino-acid sequence (Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val) derived from a fragment of body-protection compound found in gastric juice. It survives gastric acid that would destroy most peptides.
Animal models show: VEGFR2 upregulation accelerating angiogenesis at injury sites; modulation of nitric-oxide signaling; promotion of fibroblast migration and tendon-cell outgrowth; anti-inflammatory effects via downregulation of pro-inflammatory cytokines. The compound also stabilizes the gut-brain axis through serotonergic and dopaminergic modulation.
Potential Benefits & Side Effects
Potential Benefits
- Accelerated tendon and ligament healing in rodent models.
- Gastrointestinal protection: ulcer healing, IBD model improvements.
- Neuroprotection in models of TBI, stroke, and chemical neurotoxicity.
- Reduced muscle damage and faster recovery after eccentric exercise.
- Excellent safety profile in animal toxicology — no LD50 reached.
Side Effect Profile
- Generally well-tolerated; no major adverse events in published case series.
- Mild injection-site irritation possible.
- Rare reports of transient mild fatigue or nausea early.
- Theoretical angiogenesis concerns with occult malignancy.
- Long-term human safety data is limited.
Lifestyle Factors
- Inject as close to the affected area as practical when feasible.
- Maintain protein intake (1.2–1.6 g/kg/day) during active healing.
- Avoid NSAIDs during early-phase tendon/ligament healing — they may blunt repair.
- Vitamin C (500–1000 mg/day) supports collagen synthesis.
- Sleep 7–9 hours/night — most tissue repair occurs in deep sleep.
Injection Technique
- Subcutaneous most common; some literature uses intramuscular near the injury.
- Rotate injection sites if dosing twice daily.
- 90° angle with short (4–8 mm) insulin needle.
- Bring solution to room temperature before injecting.
- Hold 5 seconds after full plunger depression.